Vaccines in care homes study report

The Vivaldi 2 study, led by University College London, was set up in June 2020 to investigate SARS-CoV-2 transmission, infection outcomes, and immunity in residents and staff in care homes in England. Between 8 December 2020 and 15 March 2021 the study compared vaccinated and unvaccinated care home residents in England by using routine asymptomatic polymerase chain reaction (PCR) testing. Of 10,412 residents, 9,160 were vaccinated with either the Oxford/AstraZeneca or Pfizer vaccines, and PCR test results were used to compare the number of infections occurring in vaccinated and unvaccinated groups in order to estimate the effects of a first vaccine dose.

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